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Fmoc-Thr(Trt)-OH CAS 133180-01-5
Synonym(s)：N-α-Fmoc-O-trityl-L-threonine
Catalog Number:BRS01142
|
CAS Number |
133180-01-5 |
|
Molecular Formula |
C38H33NO5 |
|
Molecular Weight |
583.7 |
|
Purity by HPLC |
≥98.00% |
Description
The Trt protecting group can be selectively removed using 1% TFA in dichloromethane, with silanes as scavengers, while tBu-type protecting groups remain intact.
Resin-bound Hse(Trt), Ser(Trt), Thr(Trt), and Tyr(Clt) serve as versatile building blocks for on-resin side-chain modifications, including phosphorylation, sulfonation, and PEGylation.
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