During the drying process of polypeptide products, especially when using a low-temperature spray dryer, there are several important precautions:
Temperature control: Temperature control is crucial during the drying process. The low-temperature spray dryer ensures that the drying process is completed at a lower temperature by precisely controlling the temperature and humidity in the drying chamber, so as to avoid the damage of high temperature to the biological activity of polypeptides.
Spray atomization: polypeptide solution is atomized into tiny droplets by high-pressure spray to increase surface area to promote water evaporation. This process requires ensuring that the droplet size is appropriate for effective drying without affecting the structure of the peptide
Humidity management: In addition to temperature, humidity also needs to be precisely managed to ensure drying effectiveness while maximizing the preservation of peptide biological activity and stability
Proper execution of these steps is crucial for ensuring the quality and performance of the final product.