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Z-Val-Phe-CHO CAS 88191-84-8
Calpain Inhibitor III
Catalog Number: BRS09001
Calpain Inhibitor III (Z-Val-Phe-aldehyde), also known as MDL 28170, is a cell-permeable and selective inhibitor of calpain, a family of calcium-dependent cysteine proteases. Calpains are involved in various cellular processes, including cytoskeletal remodeling, cell migration, and apoptosis, making their inhibitors of interest for research and therapeutic development.
Specifications
|
Sequence one letter code |
Z-V-F-CHO |
|
Sequence three letter code |
Z-Val-Phe-CHO |
|
CAS Number |
88191-84-8 |
|
Molecular Formula |
C22H26N2O4 |
|
Molecular Weight |
382.45 |
|
Modification |
C-terminal aldehyde(al), N-terminal carbobenzyloxy (Cbz) |
|
Purity |
Peak Area by HPLC ≥95% |
|
Form |
Lyophilized |
|
Long Storage |
- 20 °C or below |
| For Research Use Only. | |
References:
1.Huang, Y., & Liu, Y. (2006). Inhibition of calpain activity protects neurons from ischemia-induced injury in rats. Neurobiology of Disease, 23(2), 415-423. 2. Erickson, J. C., & Hersh, L. B. (1997). MDL 28170 and its effects on cellular calcium homeostasis and proteolysis in human T-cells. The Journal of Immunology, 159(5), 2306-2312.
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