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LL-37, Antimicrobial Peptide

LL-37, Antimicrobial Peptide

Catalog Number: BRS16154

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LL-37 is a 37-residue, amphipathic, helical antimicrobial peptide derived from the cathelicidin family, found exclusively in humans. It exhibits broad-spectrum antimicrobial activity and is expressed in various human tissues, including epithelial cells of the skin, gastrointestinal tract, testis, and respiratory tract.

 

Specifications

Sequence one letter code

LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

Sequence three letter code

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser

CAS Number

597562-32-8

Molecular Formula

C205H340N60O53

Molecular Weight

4493.6

Modification

N/a

Purity

Peak Area by HPLC ≥95%

Form

Lyophilized

Long Storage

- 20 °C or below

For Research Use Only.

 

References:

1. Dürr, U. H. N., Sudheendra, U. S., & Ramamoorthy, A. (2006). LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1758(9), 1408-1425.

 

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