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TRAP-14
Catalog Number: BRS16150
CAS Number: 137339-65-2
Synonyms: PAR-1 (1-14) (human)
Specifications
|
Sequence one letter code |
SFLLRNPNDKYEPF |
|
Sequence three letter code |
Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe |
|
CAS Number |
137339-65-2 |
|
Molecular Formula |
C81H118N20O23 |
|
Molecular Weight |
1739.95 |
|
Modification |
N/A |
|
Purity |
Peak Area by HPLC ≥95% |
|
Form |
Lyophilized |
|
Long Storage |
- 20 °C or below |
| For Research Use Only. | |
TRAP-14 binds the cleaved PAR-1 tethered ligand binding site exposed after thrombin cleavage at Arg⁴¹/Ser⁴², directly activating the receptor without proteolysis.
Reference:
1. Garcia JG, Patterson C, Bahler C, Aschner J, Hart CM, English D. Thrombin receptor activating peptides induce Ca²⁺ mobilization, barrier dysfunction, prostaglandin synthesis, and platelet-derived growth factor mRNA expression in cultured endothelium. J Cell Physiol. 1993 Sep;156(3):541–549. doi:10.1002/jcp.1041560313.
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