Methylated Peptides

Methylated peptides are a common form of post-translational modifications (PTMs), including lysine, arginine, and cysteine methylation. Biorunstar has extensive experience in the synthesis of the following post-translationally modified peptides:

Arginine methylation Peptide Modification

Arginine methylated are involved in a number of different cellular processes, including transcriptional regulation, RNA metabolism and DNA damage repair. Their respective structures are shown as below:

Lysine Methylation Peptide Modification

Lysine methylation is restricted to a subset of proteins and catalysed by highly specific methyltransferases that can generate mono-, di-, and trimethylated lysines. These modifications result in changes in protein : protein interactions, chromatin structure and gene expression. Their respective structures are shown as below:

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