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E[c(RGDfK)]2

Catalog Number: BRS16053

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E[c(RGDfK)]₂ is a dimeric peptide containing the RGD sequence, used as an integrin ligand for radiolabeling and positron emission tomography (PET) imaging. It is applied in vascular and tumor research to study angiogenesis and integrin-related processes.

Specifications

Sequence one letter code	E[c(RGDfK)]2
Sequence three letter code	Glu[cyclo (Arg-Gly-Asp-d-Phe-Lys)]2
CAS Number	N/A
Molecular Formula	C59H87N19O16
Molecular Weight	1318.47
Modification	Cyclization
Purity	Peak Area by HPLC ≥95%
Form	Lyophilized
Long Storage	- 20 °C or below
For Research Use Only.

References:

1. Lopez-Rodriguez, V., Gaspar-Carcamo, R. E., Pedraza-Lopez, M., Rojas-Calderon, E. L., Arteaga de Murphy, C., Ferro-Flores, G., & Avila-Rodriguez, M. A. (2015). Preparation and preclinical evaluation of 66Ga-DOTA-E(c(RGDfK))₂ as a potential theranostic radiopharmaceutical. Nuclear Medicine and Biology, 42(2), 109-114.

2. Siitonen, R., Peuhu, E., Autio, A., Liljenbäck, H., Mattila, E., Metsälä, O., Käkelä, M., Saanijoki, T., Dijkgraaf, I., Jalkanen, S., Ivaska, J., & Roivainen, A. (2019). 68Ga-DOTA-E[c(RGDfK)]2 PET Imaging of SHARPIN-Regulated Integrin Activity in Mice. Journal of Nuclear Medicine, 60(10), 1380–1387.

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E[c(RGDyK)]2

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